Длинные и короткие эфиры, пики, концентрация, период полувыведения

балкан, фармаком, у последнего безэфирный тест даже на масле вроде, поэтому должен быть не болючий, но сам не пробовал)))
ps не заморачивайся, ставь проп как Эльф говорил, а то с нашей организацией соревнований, вмажешься безэфирным, а на помост тебя вызовут через хз сколько. Да и инфы по безэфирным мало, вот у суспензии ппв 60-100 минут, а пик когда хз, а если на масле то нужно еще учитывать маслянное депо...

да у фармакома и суспензия теста на водичке заходила превосходно, через 5 минут уже не помнил, в какую дельту бил

по просьбам трудящихся



Источник графика:

Testosterone Action, Deficiency, Substitution
Third Edition
Edited by
E. Nieschlag University of M¨unster
H. M. Behre
University of Halle
Assistant Editor S. Nieschlag
Раздел 14.3.6.2 "Testosterone enanthate", страница 419.

это от Бамбелы? в интернете иная информация
по запросу Testosterone Suspension HALF LIFE Schedules

к примеру, так

Testosterone base (active half-life 4-6 hours)
Testosterone base (suspension) is an injectable testosterone hormone in a water base that was developed and used for decades, and is actually the first anabolic androgenic steroid made. This is the purest form of testosterone and yields 100 mg of actual testosterone. It is a pure form with no ester attached. A few things to keep in mind with suspension: The injections can be extremely painful. They can be a lot of PIP (post injection pain) when using suspension. There is also a much higher likelihood of estrogen conversion and it needs to be taken very seriously. It is used much differently than other forms of testosterone. The water-based carrier is more prone to breed infection at the injection site than oil-based preparations.

или даже так

What is the real half life of Testosterone Suspension?
There is no classic half life of aqueous Testosterone Suspension due to the nature of the various suspension particle sizes and the non existence of an ester. In other words we don’t see the same types of decay rates with blood androgen levels in non esterfied preparations that are seen in esterfied preparations. However in March of 2011 there was a pharmacokinetics study done in horses that reported a median terminal half-life of 39 hours with aqueous Testosterone Suspension.(1) The disposition of testosterone from this formulation was characterized by an initial, rapid absorption phase followed by a much more variable secondary absorption phase. There were at least two plasma testosterone concentration peaks. The first peak is almost immediate and the second peak is a whopping 7 days later on average according to the chart in the full study. The study indicates that the initial peak is from the Testosterone formulation solution and the following peak(s) from the solid material in the suspension...


вот так на лошадях)

J Vet Pharmacol Ther. 2011 Mar 2. doi: 10.1111/j.1365-2885.2011.01277.x. [Epub ahead of print]

An interlaboratory study of the pharmacokinetics of testosterone following intramuscular administration to Thoroughbred horses.

Moeller BC, Sams RA, Guinjab J, Szabo N, Colahan P, Stanley SD.

Source

K.L. Maddy Equine Analytical Chemistry Laboratory, California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California at Davis, Davis, CA, USA Florida Racing Laboratory, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Gainesville, FL, USA.

Abstract

Moeller, B. C., Sams, R. A., Guinjab, J., Szabo, N., Colahan, P., Stanley, S. D.

An interlaboratory study of the pharmacokinetics of testosterone following intramuscular administration to Thoroughbred horses. J. vet. Pharmacol. Therap. doi: 10.1111/j.1365-2885.2011.01277.x.

Testosterone is an anabolic androgenic steroid (AAS) that is endogenously produced by both male and female horses that also has the potential for abuse when administered exogenously to race horses. To recommend appropriate withdrawal guidelines so that veterinarians can discontinue therapeutic use prior to competition, the pharmacokinetics and elimination of testosterone were investigated. An aqueous testosterone suspension was administered intramuscularly in the neck of Thoroughbred horses (n = 20). The disposition of testosterone from this formulation was characterized by an initial, rapid absorption phase followed by a much more variable secondary absorption phase. The median terminal half-life was 39 h. A second focus of this study was to compare the testosterone concentrations determined by two different laboratories using a percentage similarity model with a coefficient of variation of 16.5% showing good agreement between the two laboratories results. Based on the results of this study, a withdrawal period of 30 days for aqueous testosterone administered IM is recommended.

© 2011 Blackwell Publishing Ltd.

4-6 часов как то правдоподобнее выглядит
чем 60 минут...если б еще в вену и то мало как то)

согласен, просто привел из, того что было под рукой.

а этого вообще не понял
как то уж слишком через чур

то, как я понял лошадей на допинг ловили после месяца

просто, по запросу выше совсем иные периоды для суспензии, тоесть
опять не доказано

Ну я ж не утверждаю, сам сказал, что ППВ не нашел.
Но для суспензии - это одно, а изначально говорили для тестостерона уже в плазме. Т.е. стадию рассасывания суспензии опускаем.
Мы ж прикидывали, реально ли за счет снижения выработки тестостерона существенно понизить его уровень за 40 минут.

Есть гормоны, которые вообще считанные минуты "живут", потом разрушаются. Сейчас сходу примерами не закидаю, да и не спец я в этой теме, так, читал случайно, без особого интереса.

аналогично
просто портосим